Summary: Analysis of The Cancer Genome Atlas and other published data of head and neck squamous cell carcinoma (HNSCC) reveals somatic alterations of the Hippo-YAP pathway in approximately 50% of HNSCC.Better strategies to target the YAP1 transcriptional complex are sought.Here, we show that FAT1, an upstream inhibitor of YAP1, is mutated either by

Abstract The effect of casino proximity and Pastry Tip Sets time on poverty levels in New York City examines levels of poverty over a 5-year duration for urban casino communities under the theoretical dimensions of exposure and adaption.Links between casino proximity and problem gambling or other gambling-related problems that could adversely impac

In the last decades, geography teachers have been trying to figure out how Condoms to adopt GIS (Geographic Information Systems) tools for their high school classes.Predominantly, teachers have come to use commercial versions.Lately, it has been QGIS getting more attention, especially in environments where teachers do not have access to sufficient

The tunnel lining systems act as lines of defence against the forces and geotechnical situations.The use of precast concrete tunnel linings (PCTLs) has been pca display escalating due to its effective and economical installation process.The tunnels usually suffer from the premature deterioration due to corrosion of the reinforcement and thus need m